Product Description

CTGE5 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17185-50, ES17185-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes s receptor in the endoplasmic reticulum, which plays a role in the export of large pre-chylomicrons and pre-very low density lipoproteins (pre-VLDLs). Three major classes of transcripts are generated from this gene- melanoma inhibitory activity 2-specific transcripts, cTAGE family member 5-specific transcripts and transcripts that include exons from both these transcript species (TANGO1-like or TALI). Additionally, alternative splicing in these transcripts results in multiple transcript variants encoding multiple isoforms. [provided by RefSeq, Sep 2016],

Reactivity: Human, Mouse

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CTGE5 AA range: 253-303

Isotype: IgG

Target: CTGE5

Specificity: This antibody detects endogenous levels of CTGE5 at Human/Mouse

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 88kD

Function: Disease: Autoantigen found several cancer types, including benign meningioma and cutaneous T-cell lymphoma (CTCL). Isoform 5A and isoform 5B are recognized by patients' sera with tumor specimen of various origins
Disease: Tumor-associated antigen found in several cutaneous T-cell lymphoma (CTCL). Also found in colorectal and breast carcinomas, head and neck squamous cell carcinomas and melanoma
Function: Tumor-associated antigen
Sequence Caution: Translation N-terminally extended
Similarity: Belongs to the cTAGE family
Tissue Specificity: At the protein level, isoform 5A is expressed only in testis. Other isoforms are expressed in several other normal tissues, including brain, muscle and cranial skin. Isoform 5A (at the protein level) and isoform 5B are expressed in cutaneous T-cell lymphoma (CTCL) cell lines, colorectal carcinomas, breast carcinomas and melanoma. Isoform 5B, but not isof

Subcellular Location: endoplasmic reticulum membrane, membrane, integral component of membrane, endoplasmic reticulum exit site,

Storage and Stability: -20°C/1 year

Gene Name: CTAGE5 MEA11 MEA6 MGEA11 MGEA6

Protein Name: CTGE5

Mouse SwissProt Number: Q8R311

Research Use Only