CYP51A1 Rabbit pAb - A13485

CYP51A1 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A13485-20, A13485-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: WB, IHC-P, IF/ICC, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 57kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 1595

SWISS: Q16850

Alternate Names: LDM; CP51; CYP51; CYPL1; P450L1; P450-14DM; CYP51A1

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:2000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Signal Transduction, Endocrine Metabolism, Mitochondrial metabolism, Lipid Metabolism, Cholesterol Metabolism, Lipases, Drug metabolism, Cardiovascular, Lipids.

NCBI Alias: CYP51A1

Research Use Only