Product Description

CYTSA Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES17031-50, ES17031-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a coiled-coil domain containing protein. The encoded protein may play a critical role in actin-cytoskeletal reorganization during facial morphogenesis. Mutations in this gene are a cause of oblique facial clefting-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified, but it is thought to be non-coding. [provided by RefSeq, Jun 2013],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human CYTSA AA range: 150-200

Isotype: IgG

Target: CYTSA

Specificity: This antibody detects endogenous levels of CYTSA at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 123kD

Function: Function: Involved in cytokinesis and spindle organization
Similarity: Belongs to the cytospin-A family
Similarity: Contains 1 CH (calponin-homology) domain

Subcellular Location: Cytoplasm, cytoskeleton Cytoplasm, cytoskeleton, spindle Cell junction, gap junction Colocalizes with acetylated alpha-tubulin, gamma-tubulin and F-actin Also observed in a ring around gamma-tubulin containing centrioles possibly in the microtubule organizing center

Storage and Stability: -20°C/1 year

Gene Name: SPECC1L CYTSA KIAA0376

Protein Name: CYTSA

Mouse Gene ID: 74392

Mouse SwissProt Number: Q2KN98

Rat Gene ID: 361828

Rat SwissProt Number: Q2KN99

Research Use Only