Product Description

DCI Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES3959-50, ES3959-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, IHC, IF, ELISA

Alternate Names: ECI1, DCI, Enoyl-CoA delta isomerase 1, mitochondrial, 3,2-trans-enoyl-CoA isomerase, Delta(3),Delta(2)-enoyl-CoA isomerase, D3,D2-enoyl-CoA isomerase, Dodecenoyl-CoA isomerase

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from DCI. at AA range: c-terminal

Isotype: IgG

Target: DCI

Specificity: DCI Polyclonal Antibody detects endogenous levels of DCI protein.

Dilution: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in liver (at protein level),

Observed Band (KD): 30kD

Fields: Fatty acid degradation

Function: Catalytic Activity: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA
Function: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species
Pathway: Lipid metabolism, fatty acid beta-oxidation
Similarity: Belongs to the enoyl-CoA hydratase/isomerase family
Subunit: Homotrimer

Subcellular Location: Mitochondrion matrix

Storage and Stability: -20°C/1 year

Gene Name: ECI1

Protein Name: Enoyl-CoA delta isomerase 1 mitochondrial

Mouse SwissProt Number: P42125

Research Use Only