Product Description

DiMethyl-Histone H3 (Lys4) Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS43180-50, BS43180-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, ChIP

Alternate Names: H3K4me, H3 histone, HIST1H3A, Histone cluster 1, H3a

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Methylated

Immunogen: A synthetic methyl-peptide corresponding to residues surrounding Lys4 of human Histone H3

Dilution: WB: 1:1000 IHC: 1:1000 ICC/IF: 1:200 ChIP: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 17 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P68431

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only