DNA pol δ cat (D1091) Polyclonal Antibody-BS3850

DNA pol δ cat (D1091) Polyclonal Antibody

Catalogue Numbers:BS3850-50, BS3850-100

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Swiss-Prot: P28340

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: IHC

All Applications: IHC: 1:50~1:200

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II, and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non-coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. Pol II is the central component of the basal RNA polymerase II transcription machinery. Pols are composed of mobile elements that move relative to each other. In Pol II, POLR2F/RPB6 is part of the clamp element and togther with parts of RPB1 and RPB2 forms a pocket to which the RPB4-RPB7 subcomplex binds (By similarity).

Purification and Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Bioworld Molecular Weight: ~ 125 kDa

Specificity: NA pol δ cat (D1091) polyclonal antibody detects endogenous levels of CNA pol δ cat protein.

Note: For research use only, not for use in diagnostic procedure.
Alternative Name: DNA polymerase delta catalytic subunit; DNA polymerase subunit delta p125; POLD1; POLD; DNA pol δ p125; DNA polδ p125

Immunogen: Synthetic peptide, corresponding to amino acids 1060-1110 of Human DNA pol δ cat.

Conjugate: Unconjugated

Modification: Unmodified