Product Description

DOCK2 Polyclonal Antibody

Sizes: 120μL, 200μL

Catalogue Numbers: E-AB-67583-120, E-AB-67583-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: DOCK2

Target Synonym: DOCK2; IMD40

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Mouse

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q92608

Background: The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human DOCK2 (NP_004937.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:1000

Calculated MW: 38kDa/211kDa

Observed MW: 240kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only