Product Description

Dyrk4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES7879-50, ES7879-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes an enzyme that belongs to a conserved family of serine/threonine protein kinases. Members of this dual specificity kinase family are thought to function in the regulation of cell differentiation and proliferation, survival, and in development. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Aug 2013],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: WB, ELISA

Alternate Names: DYRK4, Dual specificity tyrosine-phosphorylation-regulated kinase 4

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from Dyrk4. at AA range: 350-430

Isotype: IgG

Target: Dyrk4

Specificity: Dyrk4 Polyclonal Antibody detects endogenous levels of Dyrk4 protein.

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Brain, Kidney, Lung, Testis,

Observed Band (KD): 60kD

Function: Catalytic Activity: ATP + a protein = ADP + a phosphoprotein
Cofactor: Magnesium
Function: Possible non-essential role in spermiogenesis
PTM: Autophosphorylated on tyrosine residues
Similarity: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MNB/DYRK subfamily
Similarity: Contains 1 protein kinase domain

Subcellular Location: [Isoform 1]: Cytoplasm, [Isoform 4]: Cytoplasm Nucleus

Storage and Stability: -20°C/1 year

Gene Name: DYRK4

Protein Name: Dual specificity tyrosine-phosphorylation-regulated kinase 4

Mouse SwissProt Number: Q8BI55

Research Use Only