Product Description

EIF3I Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES16771-50, ES16771-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human EIF3I AA range: 100-150

Isotype: IgG

Target: EIF3I

Specificity: This antibody detects endogenous levels of EIF3I at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 36kD

Function: Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2: GTP: methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation
mass spectrometry: PubMed: 17322308,mass spectrometry: PubMed: 18599441,PTM: Phosphorylated by TGF-beta type II receptor
Similarity: Belongs to the eIF-3 subunit I family
Similarity: Contains 5 WD repeats
Subunit: Component of the eukaryotic

Subcellular Location: Cytoplasm

Storage and Stability: -20°C/1 year

Gene Name: EIF3I EIF3S2 TRIP1

Protein Name: EIF3I

Mouse Gene ID: 54709

Mouse SwissProt Number: Q9QZD9

Rat Gene ID: 682390

Rat SwissProt Number: B0BNA7

Research Use Only