Elab Fluor® 488 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7] - E-AB-F1191UL

Elab Fluor® 488 Anti-Mouse Ly6A/E(Sca-1) Antibody [D7]

Size: 100μg

Catalogue Number: E-AB-F1191UL-100

Citations, Manuals and MSDS Available upon request.

Abbreviation: Ly6A/E(Sca-1)

Target Synonym: Ly6a, Ly6, Ly-6A.2/Ly-6E.1, SCA-1, TAP,

Conjugation: Elab Fluor® 488

Host: Rat

Species Reactivity: Mouse

Application: FCM

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Isotype: Rat IgG2a, κ

Clone No.: D7

UNIProt ID: P05533

Background: Ly-6A/E, also known as Sca-1, is an 18 kD member of the Ly-6 multigene family. Ly6A/E is a glycosylphosphatidylinositol (GPI)-linked protein expressed on hematopoietic stem cells. In mice expressing the Ly-6.2 haplotype (e.g., AKR, C57BL, C57BR, DBA/2, SJL, SWR, and 129), Ly-6A/E is also expressed on peripheral B lymphocytes and thymic and peripheral T lymphocytes. Strains expressing the Ly-6.1 haplotype (e.g., BALB/c, CBA, C3H/He, DBA/1, and NZB) have low Ly-6A/E expression on resting peripheral lymphocytes. The expression of Ly-6A/E on lymphocytes is upregulated upon activation from both Ly6.1 and Ly6.2 haplotype mice. Ly-6A/E is thought to be involved in the regulation of both T and B cell responses.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F09833L

Buffer: Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

GeneID: 110454

Storage: This product can be stored at 2-8°C for 12 months. Please protect from prolonged exposure to light and do not freeze.

Shipping: Ice bag