Product Description

EP400 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES16740-50, ES16740-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Reactivity: Human, Mouse

Host: Rabbit

Applications: IHC, IF

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human EP400 AA range: 2057-2107

Isotype: IgG

Target: EP400

Specificity: This antibody detects endogenous levels of EP400 at Human/Mouse

Dilution: IHC-p 1：50-200

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Ubiquitously expressed,

Molecular Weight (Da): 347kD

Function: Caution: The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data
Function: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity
Sequence Caution: Contaminating sequence. Potential poly-A sequence
Sequence Caution: Intron retention
similar

Subcellular Location: Nucleus

Storage and Stability: -20°C/1 year

Gene Name: EP400 CAGH32 KIAA1498 KIAA1818 TNRC12

Protein Name: EP400

Mouse Gene ID: 75560

Mouse SwissProt Number: Q8CHI8

Research Use Only