Product Description

Estrogen Receptor α (ER) Monoclonal Antibody

Sizes: 100μL, 200μL

Catalogue Numbers: PA6541-100, PA6541-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Estrogen Receptor α(ER)

Target Synonym: DKFZp686N23123, ER alpha, ER, ER-alpha, Era, ESR, ESR1, ESR1, ESRA, Estradiol receptor, Estrogen nuclear receptor alpha, Estrogen receptor 1, Estrogen receptor alpha 3*, 4, 5, 6, 7*/822 isoform, Estrogen receptor alpha, Estrogen receptor alpha delta 3*, 4, 5, 6, 7*, 8*/941 isoform, Estrogen receptor alpha delta 3*, 4, 5, 6, 7*/819 2 isoform, Estrogen receptor alpha delta 4 +49 isoform, Estrogen receptor alpha delta 4*, 5, 6, 7*/654 isoform, Estrogen receptor alpha delta 4*, 5, 6, 7, 8*/901 isoform, Estrogen receptor alpha E1 E2 1 2, Estrogen receptor alpha E1 N2 E2 1 2, Estrogen receptor, ESTRR, NR3A1, Nuclear receptor subfamily 3 group A member 1

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human

Application: IHC-P

Clonality: Monoclonal

Clone No.: YN00806m

UNIProt ID: P03372

Background: Estrogen receptor (ER) is a steroid receptor of nuclear receptor superfamily, which consists of 553 aa. ER have three domains: the central domain of DNA binding, the hormone binding domain of C-terminal and the transcriptional activation domain of N-terminal. ER is involved in the regulation of female sex hormones, mainly mediating the growth, differentiation and other functions of 17 (E2) on several target tissues . ER α is expressed in the nucleus of epithelial cells of normal breast and endometrium, and also in breast cancer. Immunohistochemistry analysis showed that the overall survival rate of steroid positive prediction is good. RE α can also be used as a tumor marker combined with anti-progesterone receptor.

The concentrated should be stored at -20°C protecting from light,The RTU should be stored at 2~8°C protecting from light (Do not freeze).Valid for 12 months.

Shipping: Ice bag

Research Use Only