Product Description

EXOC4 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES16655-50, ES16655-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human EXOC4 AA range: 512-562

Isotype: IgG

Target: EXOC4

Specificity: This antibody detects endogenous levels of EXOC4 at Human/Mouse/Rat

Dilution: WB 1：500-2000

Purification: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Molecular Weight (Da): 107kD

Fields: Salmonella infection

Function: Function: Component of the exocyst complex involved in the docking of exocystic vesicles with fusion sites on the plasma membrane
Similarity: Belongs to the SEC8 family
Subunit: The exocyst complex is composed of EXOC1, EXOC2, EXOC3, EXOC4, EXOC5, EXOC6, EXOC7 and EXOC8

Subcellular Location: Midbody, Midbody ring Cell projection Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214) Localizes at the leading edge of migrating cells (By similarity)

Storage and Stability: -20°C/1 year

Gene Name: EXOC4 KIAA1699 SEC8 SEC8L1

Protein Name: EXOC4

Mouse Gene ID: 20336

Mouse SwissProt Number: O35382

Rat Gene ID: 116654

Rat SwissProt Number: Q62824

Research Use Only