Product Description

F8 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS49234-50, BS49234-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes coagμlation factor VIII, which participates in the intrinsic pathway of blood coagμlation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circμlates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes mμltiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagμlant activity. Defects in this gene resμlts in hemophilia A, a common recessive X-linked coagμlation disorder. [provided by RefSeq, Jμl 2008]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC

Alternate Names: AHF, F8B, F8C, HEMA, FVIII, THPH13, DXS1253E

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human F8

Dilution: WB: 1:1000 IHC: 1:500 ICC/IF: 1:500 FC: 1:200

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 267 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P00451

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only