Fatty Acid Synthase (FASN) Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0461-20, A0461-100
Citations, Manuals and MSDS Available upon request.
Background: The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.
Category: Polyclonal Antibodies
Applications: WB, IHC-P, IF/ICC, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 273kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 2194
SWISS: P49327
Alternate Names: FAS; OA-519; SDR27X1; Fatty Acid Synthase (FASN)
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 IHC-P, 1:50 - 1:200 IF/ICC, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, RNA Binding, Cancer, Tumor biomarkers, Signal Transduction, Endocrine Metabolism, Lipid Metabolism, AMPK Signaling Pathway, Neuroscience, Cardiovascular, Lipids, Fatty Acids.
NCBI Alias: FASN
Research Use Only