Product Description

FGFR3 Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46626-50, BS46626-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A fμll-length representative protein woμld consist of an extracellμlar region, composed of three immunoglobμlin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellμlar portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals,μltimately influencing mitogenesis and differentiation. This particμlar family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and mμltiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC

Alternate Names: ACH, CEK2, JTK4, CD333, HSFGFR3EX

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human FGFR3

Dilution: WB: 1:2000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 125 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P22607

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only