FineTest®488 Anti-Mouse CD40 Antibody (FGK4.5/FGK45)
Sizes: 50T, 100T
Catalogue Numbers: F488-30021-50, F488-30021-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse CD40
Form: Liquid
Conjugation: FineTest®488
Conjugation Information: FineTest® 488 is designed to be excited by the Blue laser (488 nm) and detected using an optical filter centered near 520 nm (e.g., a 525/40 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: FGK4.5/FGK45
Isotype: IgG2a, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD40 is a 48 kD type I transmembrane glycoprotein also known as Bp50. It is a member of the tumor necrosis factor receptor (TNFR) superfamily and is expressed on B cells, basal epithelial cells, macrophages, follicular dendritic cells, endothelial cells, and a subset of CD34+ hematopoietic progenitors. CD40 regulates B cell development/maturation, Ig isotype switching and, in combination with other signals such as IL-4, protects B cells from surface Ig-induced apoptosis and promotes proliferation. Interaction of CD40 with its ligand CD154 (gp39), which is expressed on activated T cells, is important in costimulation and immune regulation.
Synonyms: B-cell surface antigen CD40|Bp50|CD40|CD40L receptor|Cd40|Tnfrsf5|Tumor necrosis factor receptor superfamily member 5
Uniprot ID: P27512
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 21939
Category: Flow cytometryometry Antibodies
Research Use Only