FineTest®647 Anti-Human/Mouse CD44 Antibody (IM7)
Sizes: 25μg, 100μg
Catalogue Numbers: F647-30083U-25, F647-30083U-100
Citations, Manuals and MSDS Available upon request.
Target: Human/Mouse CD44
Form: Liquid
Conjugation: FineTest®647
Conjugation Information: FineTest® 647 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 670 nm (e.g., a 660/20 nm bandpass filter).
Host: Rat
Clonality: Monoclonal
Clone ID: IM7
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD44 is a 80-95 kD glycoprotein also known as Hermes, Pgp1, H-CAM, or HUTCH. It is expressed on all leukocytes, endothelial cells, hepatocytes, and mesenchymal cells. As B and T cells become activated or progress to the memory stage, CD44 expression increases from low or mid levels to high levels. Thus, CD44 has been reported to be a valuable marker for memory cell subsets. High CD44 expression on Treg cells has been associated with potent suppressive function via high production of IL-10. CD44 is an adhesion molecule involved in leukocyte attachment to and rolling on endothelial cells, homing to peripheral lymphoid organs and to the sites of inflammation, and leukocyte aggregation.
Synonyms: CD44 antigen| CD44| CDw44| Epican| Phagocytic glycoprotein 1| PGP-1| Phagocytic glycoprotein I| PGP-I| CD44| LHR| MDU2| MDU3| MIC4
Uniprot ID: P15379, P16070
Reactivity: Human/Mouse
Tested Application: FC
Recommended Dilution: Each lot of this antibody is quality control tested by Flow cytometryometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1μg/10⁶ cells in 100 μL volume].
Gene ID: 12505, 960
Category: Flow cytometryometry Antibodies
Research Use Only