FineTest®700 Anti-Mouse IL-17A Antibody (17F3)
Sizes: 50T, 100T
Catalogue Numbers: F700-30267-50, F700-30267-100
Citations, Manuals and MSDS Available upon request.
Target: Mouse IL-17A
Form: Liquid
Conjugation: FineTest®700
Conjugation Information: FineTest® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: 17F3
Isotype: IgG1, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: The 17F3 Monoclonal Antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 Antibody has been shown to neutralize IL-17A in vivo.
Synonyms: Ctla8|Il17a|Interleukin-17A
Uniprot ID: Q62386
Reactivity: Mouse
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 16171
Category: Flow cytometryometry Antibodies
Research Use Only