FineTest®Violet 450 Anti-Human CD326/EpCAM Antibody (9C4)
Sizes: 20T, 100T
Catalogue Numbers: FV450-30140-20, FV450-30140-100
Citations, Manuals and MSDS Available upon request.
Target: Human CD326/EpCAM
Form: Liquid
Conjugation: FineTest®Violet 450
Conjugation Information: FineTest® Violet 450 is designed to be excited by the violet laser (405 nm) and detected using an optical filter centered near 450 nm (e.g., a 450/45 nm bandpass filter).
Host: Mouse
Clonality: Monoclonal
Clone ID: 9C4
Isotype: IgG2b, κ
Storage: PBS with 0. 1% sodium azide, 1%BSA, pH 7.3, 2-8℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background: CD326 is also known as Ep-CAM, tumor associated calcium signal transducer 1, epithelial cell surface antigen, epithelial glycoprotein 2, EGP2, adenocarcinoma associated antigen, and TROP1. CD326 is a type I transmembrane protein containing six disulfide bridges and one THYRO domain. This cell surface glycosylated 40 kD protein is highly expressed in bone marrow, colon, lung, and most normal epithelial cells and is expressed on carcinomas of gastrointestinal origin. Recently, it has been reported that CD326 expression occurs during the early steps of erythrogenesis. CD326 functions as a homotypic calcium-independent cell adhesion molecule and is believed to be involved in carcinogenesis by its ability to induce genes involved in cellular metabolism and proliferation. CD326 antigen is an immunotherapeutic target for the treatment of human carcinomas.
Synonyms: TROP1|Ep-CAM|EpCAM|GA733-2|M1S2|M4S1|MIC18|TACSTD1
Uniprot ID: P16422
Reactivity: Human
Tested Application: FC
Recommended Dilution: Volume per test: 5μL. Each lot of this antibody is quality control tested by Flow cytometryometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Gene ID: 4072
Category: Flow cytometryometry Antibodies
Research Use Only