Frizzled-4 Polyclonal Antibody - BT-AP03360

Frizzled-4 Polyclonal Antibody

Sizes: 20μL, 50μL, 100μL

Catalogue Numbers: BT-AP03360-20, BT-AP03360-50, BT-AP03360-100

Citations, Manuals and MSDS Available upon request.

Background: FZD4 (frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

Research Areas: Signal Transduction

Target Protein: FZD4

Applications: IF, ELISA

Reactivity: Human, Mouse, Rat

Clonality: Polyclonal

Host: Rabbit

Isotype: IgG

Full Product Name: Frizzled-4 Antibody

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage: -20°C for 1 year

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Molecular Weight (Da): 59881

UniProt Accession: Human: Q9ULV1; Mouse: Q61088; Rat: Q9QZH0

Synonyms: FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

GeneID: Human: 8322; Mouse: 14366; Rat: 64558

Research Use Only