FTO Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A18672-20, A18672-100
Citations, Manuals and MSDS Available upon request.
Background: Predicted to enable 2-oxoglutarate-dependent dioxygenase activity and ferrous iron binding activity. Acts upstream of or within several processes, including cilium assembly; left/right pattern formation; and positive regulation of canonical Wnt signaling pathway. Predicted to be located in cytoplasm and nuclear speck. Human ortholog (s) of this gene implicated in obesity. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase).
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Observed Molecular Weight: 60kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 553363
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Neuroscience Neurology process MetabolismCardiovascular Atherosclerosis Lipoprotein metabolismCardiovascular Atherosclerosis Lipid transportCardiovascular Atherosclerosis Diabetes associatedMetabolism Pathways and Processes Metabolic signaling pathways Lipid and lipoprotein metabolism Lipoprotein metabolismMetabolism Types of disease DiabetesMetabolism Types of disease ObesityMetabolism Types of disease CancerMetabolism Types of disease Heart diseaseMetabolism Types of disease Metabolic disorders
NCBI Alias: fto
Research Use Only