Product Description

Fucokinase Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES2379-50, ES2379-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: fucokinase(FUK) Homo sapiens The protein encoded by this gene belongs to the GHMP (galacto-, homoserine, mevalonate and phosphomevalonate) kinase family and catalyzes the phosphorylation of L-fucose to form beta-L-fucose 1-phosphate. This enzyme catalyzes the first step in the utilization of free L-fucose in glycoprotein and glycolipid synthesis. L-fucose may be important in mediating a number of cell-cell interactions such as blood group antigen recognition, inflammation, and metastatis. While several transcript variants may exist for this gene, the full-length nature of only one has been described to date. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Monkey

Host: Rabbit

Applications: WB, IF, ELISA

Alternate Names: FUK, L-fucose kinase, Fucokinase

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human FUK. AA range:11-60

Isotype: IgG

Target: Fucokinase

Specificity: Fucokinase Polyclonal Antibody detects endogenous levels of Fucokinase protein.

Dilution: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed in fibroblasts,

Observed Band (KD): 110kD

Fields: Fructose and mannose metabolism, Amino sugar and nucleotide sugar metabolism, Metabolic pathways, Biosynthesis of nucleotide sugars

Function: Catalytic Activity: ATP + L-fucose = ADP + beta-L-fucose 1-phosphate
Function: Takes part in the salvage pathway for reutilization of fucose from the degradation of oligosaccharides
Similarity: Belongs to the GHMP kinase family

Subcellular Location: cytoplasm, cytosol,

Storage and Stability: -20°C/1 year

Gene Name: FUK

Protein Name: L-fucose kinase

Research Use Only