GABAA Rα1 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25177-50, RA25177-100
Citations, Manuals and MSDS Available upon request.
Background: gamma-aminobutyric acid type A receptor alpha1 subunit (GABRA1) Homo sapiens This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene cause juvenile myoclonic epilepsy and childhood absence epilepsy type 4. Multiple transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: GABRA1; Gamma-aminobutyric acid receptor subunit alpha-1; GABA (A) receptor subunit alpha-1
Applications: WB; IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 2554
Protein MW (KDa): 50
SWISS: P14867
Source: Rabbit
Research Use Only