GABAA Rα4 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25178-50, RA25178-100
Citations, Manuals and MSDS Available upon request.
Background: gamma-aminobutyric acid type A receptor alpha4 subunit (GABRA4) Homo sapiens Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. This gene encodes subunit alpha-4, which is involved in the etiology of autism and eventually increases autism risk through interaction with another subunit, gamma-aminobutyric acid receptor beta-1 (GABRB1) . Alternatively spliced transcript variants encoding different isoforms have been found in this gene.[provided by RefSeq, Feb 2011],
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Alternative Names: GABRA4; Gamma-aminobutyric acid receptor subunit alpha-4; GABA (A) receptor subunit alpha-4
Applications: WB; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 2557
Protein MW (KDa): 60
SWISS: P48169
Source: Rabbit
Research Use Only