GAD65/GAD2 Rabbit pAb - A0971

GAD65/GAD2 Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A0971-20, A0971-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.

Category: Polyclonal Antibodies

Applications: WB, IF-P, ELISA

Cross-reactivity: Human, Mouse, Rat

Protein Weight: 65kDa

Observed Molecular Weight: 60kDa

Immunogen: Recombinant protein (or fragment)

Species: Human

GeneID: 2572

SWISS: Q05329

Alternate Names: GAD65; GAD65/GAD2

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol,  preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis),  pH 7.3.

Recommended Dilutions: WB, 1:500 - 1:1000 IF-P, 1:50 - 1:200 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Cancer, Endocrine Metabolism, Amino acid metabolism, Neuroscience.

NCBI Alias: GAD2

Research Use Only