GALNT4 Polyclonal Antibody - E-AB-92585

GALNT4 Polyclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-92585-60, E-AB-92585-120, E-AB-92585-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: GALNT4

Target Synonym: GALNT4; GALNAC-T4; GALNACT4

Conjugation: Unconjugated

Host: Rabbit

Species Reactivity: Human, Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

UNIProt ID: Q8N4A0

Background: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.

Concentration: 1mg/mL

Immunogen: Recombinant fusion protein of human GALNT4

Buffer: PBS with 0.01% thiomersal, 50% glycerol, pH7.3.

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 45kDa/66kDa

Observed MW: 67KDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only