GCS-β-2 Polyclonal Antibody
Sizes: 50μL, 100μL
Catalogue Numbers: RA25278-50, RA25278-100
Citations, Manuals and MSDS Available upon request.
Background: Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.
Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Instructions: -20°C/1 year
Recommended dilutions: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Alternative Names: GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2
Applications: IHC-p; IF (paraffin section) ; ELISA
Species Cross-Reactivity: Human; Mouse; Rat
GeneID (Human): 2974
Protein MW (KDa): 70
SWISS: O75343
Source: Rabbit
Research Use Only