GCS-β-2 rabbit pAb - ES5691

GCS-β-2 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5691-50, ES5691-100

Citations, Manuals and MSDS Available upon request.

Background: Nitric oxide-sensitive guanylyl cyclase is a heterodimeric enzyme consisting of an alpha and a beta subunit. The enzyme converts GTP into the second messenger cGMP and plays a major role in the cardiovascular system as a receptor for nitric oxide. Unlike other guanylyl cyclases, GUCY1B2 contains an 86-amino acid C-terminal extension with a consensus sequence for isoprenylation/carboxymethylation.

Alternate Name: GUCY1B2; Guanylate cyclase soluble subunit beta-2; GCS-beta-2

Source: Rabbit

Applications: IHC; IF; ELISA

Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human GCS-beta-2. AA range:53-102

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 70kD

Human Gene ID: 2974

Human SWISS Prot NO: O75343

Subcellular Location: Cytoplasm

Research Use Only