Product Description

GIMAP4 Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS61682-50, BS61682-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regμlation of lymphomyeloid cell survival. GIMAP4 (GTPase IMAP family member 4), also known as IMAP4 (immunity-associated protein 4) and IAN1 (immunityassociated nucleotide 1 protein), is a 329 amino acid protein that contains 5 motifs that are conserved in GTP-binding proteins and a C-terminal coiledcoiled region that may be responsible for protein-protein interactions. GIMAP4 exhibits intrinsic GTPase activity that is highly dependent on magnesium concentration to bind GDP. Showing differential regμlation during T-helper cell differentiation, GIMAP4 appears to regμlate the apoptosis of T cells. GIMAP4 is specifically expressed in resting T and B lymphocytes and its protein expression is appreciably decreased upon T or B lymphocyte activation.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: GTPase IMAP family member 4, Immunity-associated nucleotide 1 protein, IAN-1, hIAN1, Immunity-associated protein 4, GIMAP4, IMAP4, IAN1, MSTP062

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Synthetic peptide, corresponding Human GIMAP4.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: GIMAP4 polyclonal antibody detects endogenous levels of GIMAP4 protein.

Molecular Weight: ~ 37 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q9NUV9

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only