GITR/TNFRSF18 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A15625-20, A15625-100
Citations, Manuals and MSDS Available upon request.
Background: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25 (+) CD4 (+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Mouse
Protein Weight: 26kDa
Observed Molecular Weight: 30kDa
Immunogen: Recombinant protein (or fragment)
Species: Human
GeneID: 8784
SWISS: Q9Y5U5
Alternate Names: AITR; GITR; CD357; GITR-D; ENERGEN; GITR/TNFRSF18
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Cancer, Signal Transduction, Cell Biology Developmental Biology, Growth factors, Immunology Inflammation, CDs, Cytokines, NF-kB Signaling Pathway, Cell Intrinsic Innate Immunity Signaling Pathway.
NCBI Alias: TNFRSF18
Research Use Only