Product Description

GPDA Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9149-50, ES9149-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 210-290

Isotype: IgG

Target: GPDA

Specificity: GPDA Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Expressed in liver (at protein level),

Observed Band (KD): 38kD

Fields: Glycerophospholipid metabolism

Function: Catalytic Activity: sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + NADH
Enzyme Regulation: Inhibited by zinc ions and sulfate
Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family
Subunit: Homodimer

Subcellular Location: Cytoplasm

Storage and Stability: -20°C/1 year

Gene Name: GPD1

Protein Name: Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic (GPD-C) (GPDH-C) (EC 1.1.1.8)

Mouse SwissProt Number: P13707

Rat SwissProt Number: O35077

Research Use Only