Product Description

GPR43 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES5620-50, ES5620-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the GP40 family of G protein-coupled receptors that are clustered together on chromosome 19. The encoded protein is a receptor for short chain free fatty acids and may be involved in the inflammatory response and in regulating lipid plasma levels. [provided by RefSeq, Apr 2009],

Reactivity: Human, Rat, Mouse,

Host: Rabbit

Applications: IF, ELISA

Alternate Names: FFAR2, GPR43, Free fatty acid receptor 2, G-protein coupled receptor 43

Clonality: Polyclonal

Immunogen: The antiserum was produced against synthesized peptide derived from human FFAR2. AA range:271-320

Isotype: IgG

Target: GPR43

Specificity: GPR43 Polyclonal Antibody detects endogenous levels of GPR43 protein.

Dilution: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Expression: Expressed at relatively high levels in peripheral blood leukocytes and, to lesser extent, in spleen,

Molecular Weight (Da): 37kD

Fields: cAMP signaling pathway

Function: Function: Receptor for short chain fatty acids through a G(i)-protein-mediated inhibition of adenylyl cyclase and elevation of intracellular calcium. The rank order of potency for agonists of this receptor is acetate= propionate = butyrate > pentanoate = formate
Similarity: Belongs to the G-protein coupled receptor 1 family
Tissue Specificity: Expressed at relatively high levels in peripheral blood leukocytes and, to lesser, extent, in spleen

Subcellular Location: Cell membrane, Multi-pass membrane protein

Storage and Stability: -20°C/1 year

Gene Name: FFAR2

Protein Name: Free fatty acid receptor 2

Mouse SwissProt Number: Q8VCK6

Research Use Only