Product Description

Granzyme B Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS49127-50, BS49127-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellμlar matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Mice lacking a functional copy of this gene exhibit impaired immune cell-mediated cytolysis. [provided by RefSeq, Sep 2016]

Category: Primary Antibody

Reactivity: Mouse

Host: Rabbit

Applications: WB, FC

Alternate Names: GZB, CCP1, Ctla1, Ctla-1, AI553453, CCP-1/C11

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of mouse Granzyme B

Dilution: WB: 1:1000 FC: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 28 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P04187

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only