GRB10 Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A0634-20, A0634-100
Citations, Manuals and MSDS Available upon request.
Background: The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts. Alternatively spliced transcript variants encoding different isoforms have been identified.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 67kDa
Observed Molecular Weight: 70kDa
Immunogen: Synthetic peptide
Species: Human
GeneID: 2887
SWISS: Q13322
Alternate Names: RSS; IRBP; MEG1; GRB-IR; Grb-10; GRB10
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Cell Biology Developmental Biology, Growth factors, Endocrine Metabolism, Insulin Receptor Signaling Pathway.
NCBI Alias: GRB10
Research Use Only