Product Description

Growth Hormone Receptor Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46856-50, BS46856-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellμlar signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellμlar ligand-binding domain from the mature growth hormone receptor protein. Mμltiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, FC, IP

Alternate Names: GHBP, GHIP

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide of human Growth hormone receptor

Dilution: WB: 1:1000-1:5000 FC: 1:50 IP: 1:50

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 120 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P10912

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only