GSK3α/β (phospho Tyr279/216) rabbit pAb - ES1321

GSK3α/β (phospho Tyr279/216) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES1321-50, ES1321-100

Citations, Manuals and MSDS Available upon request.

Background: glycogen synthase kinase 3 alpha (GSK3A) Homo sapiens This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011],

Alternate Name: GSK3A; Glycogen synthase kinase-3 alpha; GSK-3 alpha; Serine/threonine-protein kinase GSK3A; GSK3B; Glycogen synthase kinase-3 beta; GSK-3 beta; Serine/threonine-protein kinase GSK3B

Source: Rabbit

Applications: IF; WB; IHC; ELISA

Dilution: IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human GSK3 alpha/beta around the phosphorylation site of Tyr279/216. AA range:246-295

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 51, 46kD

Human Gene ID: 2931

Human SWISS Prot NO: P49840/P49841

Subcellular Location: mitochondrion, cytosol, beta-catenin destruction complex, postsynapse,

Research Use Only