Heme Oxygenase 1 (HO-1/HMOX1) Rabbit PolymAb®
Sizes: 20μL, 100μL
Catalogue Numbers: A28140PM-20, A28140PM-100
Citations, Manuals and MSDS Available upon request.
Background: Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family.
Category: Monoclonal Antibodies
Applications: WB, IP, IF/ICC, IF-P, IHC-P, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 33 kDa
Observed Molecular Weight: 30 kDa/35 kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human/Mouse
GeneID: 3162/15368
SWISS: P09601/P14901
Alternate Names: HO-1; HSP32; HMOX1D; bK286B10; D8Wsu38e; HO-1; HO1; Hemox; Hmox; Hsp32
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.09% Sodium azide, 0.05% BSA, 50% glycerol, pH 7.3.
Recommended Dilutions: WB, 1:5000 - 1:25000 IP, 0.5μg-4μg antibody for 200μg-400μg extracts of whole cells IF/ICC, 1:200 - 1:2000 IF-P, 1:200 - 1:2000 IHC-P, 1:5000 - 1:20000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements. For high-ratio antibody dilutions (≥1:10000) ，a sequential dilution method is strongly recommended to ensure measurement accuracy.
Research Areas: Epigenetics Nuclear Signaling, Cancer, Signal Transduction, Endocrine Metabolism, Immunology Inflammation, Neuroscience, Neurodegenerative Diseases, Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease, Cardiovascular, Blood, Hypoxia.
NCBI Alias: HMOX1
Research Use Only