Product Description

HLA-DOβ Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25966-50, RA25966-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: major histocompatibility complex, class II, DO beta (HLA-DOB) Homo sapiens HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Rabbit

Applications: WB, ELISA

Alternate Names: HLA-DOB, HLA class II histocompatibility antigen, DO beta chain, MHC class II antigen DOB

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 30

Protein Molecular Weight (kDa): 30

Storage: -20°C/1 year

Human Gene ID: 3112

Human SwissProt Number: P13765

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only