Product Description

HLA-DPα1 Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA25967-50, RA25967-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: major histocompatibility complex, class II, DP alpha 1 (HLA-DPA1) Homo sapiens HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008],

Reactivity: Human

Host: Rabbit

Applications: WB, ELISA

Alternate Names: HLA-DPA1, HLA-DP1A, HLASB, HLA class II histocompatibility antigen, DP alpha 1 chain, DP (W3), DP (W4), HLA-SB alpha chain, MHC class II DP3-alpha, MHC class II DPA1

Clonality: Polyclonal

Dilution: Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Molecular Weight: 29

Protein Molecular Weight (kDa): 29

Storage: -20°C/1 year

Human Gene ID: 3113

Human SwissProt Number: P20036

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Research Use Only