HNF4A Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A2085-20, A2085-100
Citations, Manuals and MSDS Available upon request.
Background: The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human
Protein Weight: 53kDa
Observed Molecular Weight: 52kDa
Immunogen: Synthetic peptide .
Species: Human
GeneID: 3172
SWISS: P41235
Alternate Names: TCF; HNF4; MODY; FRTS4; MODY1; NR2A1; TCF14; HNF4a7; HNF4a8; HNF4a9; NR2A21; TCF-14; HNF4alpha; HNF4A
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:500 - 1:2000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Nuclear Receptor Signaling, Protein phosphorylation, Cancer, Signal Transduction, Cell Biology Developmental Biology, Cell Adhesion, Wnt -Catenin Signaling Pathway, Endocrine Metabolism, Lipid Metabolism, Cholesterol Metabolism, AMPK Signaling Pathway, Endocrine and metabolic diseases, Diabetes, Stem Cells, Cardiovascular, Blood, Lipids.
NCBI Alias: HNF4A
Research Use Only