Product Description

HOPX Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS45412-50, BS45412-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: Atypical homeodomain protein which does not bind DNA and is required to modμlate cardiac growth and development. Acts via its interaction with SRF, thereby modμlating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (PubMed:12297045, PubMed:12297046). Acts as a co-chaperone for HSPA1A and HSPA1B chaperone proteins and assists in chaperone-mediated protein refolding (By similarity).

Category: Primary Antibody

Reactivity: Mouse, Rat

Host: Rabbit

Applications: WB, IP

Alternate Names: Hod, Hop, Ob1, Obl, Hdop, Toto, Cameo, AI848177, AW490897, 1110018K11Rik, 1200015P04Rik, 2300002F06Rik

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of mouse HOPX

Dilution: WB: 1:1000 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 12 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: Q8R1H0

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only