Human Neurogranin Rabbit pAb
Sizes: 20μL, 100μL
Catalogue Numbers: A22030-20, A22030-100
Citations, Manuals and MSDS Available upon request.
Background: Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.
Category: Polyclonal Antibodies
Applications: WB, ELISA
Cross-reactivity: Human, Mouse, Rat
Protein Weight: 8kDa
Observed Molecular Weight: 15kDa
Immunogen: Recombinant protein (or fragment) .
Species: Human
GeneID: 4900
SWISS: Q92686
Alternate Names: RC3; hng; Human Neurogranin
Source: Rabbit
Isotype: IgG
Purity: Affinity purification
Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Recommended Dilutions: WB, 1:100 - 1:500 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Research Areas: Signal Transduction, Kinase, Endocrine Metabolism, Neuroscience, Calcium Signaling.
NCBI Alias: NRGN
Research Use Only