IκB-ζ Rabbit pAb - A25250

IκB-ζ Rabbit pAb

Sizes: 20μL, 100μL

Catalogue Numbers: A25250-20, A25250-100

Citations, Manuals and MSDS Available upon request.

Background: This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS) . The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Category: Polyclonal Antibodies

Applications: IHC-P, ELISA

Cross-reactivity: Mouse

Protein Weight: 78kDa

Observed Molecular Weight: Refer to figures

Immunogen: Synthetic peptide .

Species: human

GeneID: 64332

SWISS: Q9BYH8

Alternate Names: IKBZ; INAP; MAIL; ikB-zeta; ikappaBzeta; IkappaB-zeta; I-kappa-B-zeta; NFKBIZ

Source: Rabbit

Isotype: IgG

Purity: Affinity purification

Storage: Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.

Recommended Dilutions: IHC-P, 1:500 - 1:1000 ELISA, Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.

Research Areas: Epigenetics Nuclear Signaling, Transcription Factors, Cell Biology Developmental Biology, Apoptosis, Inhibition of Apoptosis, Cell Cycle, Death Receptor Signaling Pathway, Endocrine Metabolism, Immunology Inflammation, B Cell Receptor Signaling Pathway, T Cell Rece.

NCBI Alias: NFKBIZ

Research Use Only