Product Description

ID1 Rabbit Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: ES9039-50, ES9039-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB, ELISA

Clonality: Polyclonal

Immunogen: Synthesized peptide derived from human protein. at AA range: 30-110

Isotype: IgG

Target: ID1

Specificity: ID1 Polyclonal Antibody detects endogenous levels of protein.

Dilution: WB 1:500-2000 ELISA 1:5000-20000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml,

Formlation: Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

Expression: Lung, Ovary, Placenta, Skin,

Observed Band (KD): 17kD

Fields: Rap1 signaling pathway, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells

Function: Alternative Products: Additional isoforms seem to exist,Developmental Stage: Expression correlates with proliferation in some types of cells
Function: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding
Similarity: Contains 1 basic helix-loop-helix (bHLH) domain
Subunit: Heterodimer with other HLH proteins. Interacts with COPS5

Subcellular Location: Cytoplasm Nucleus

Storage and Stability: -20°C/1 year

Gene Name: ID1 BHLHB24 ID

Protein Name: DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24) (bHLHb24) (Inhibitor of DNA binding 1)

Mouse SwissProt Number: P20067

Rat SwissProt Number: P41135

Research Use Only