Product Description

IFN-ω Polyclonal Antibody

Sizes: 50μl, 100μl

Catalogue Numbers: BS60296-50, BS60296-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, 1 IFN-β gene, 1 IFN-ω (also known as IFN-α II1) gene, and a number of IFN-ω pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent anti-viral activity. IFN-α and -β exert a variety of other biological effects, including anti-tumor and immunomodμlatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-ω is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The Type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-ω, and seems to be a mμltisubunit receptor.

Category: Primary Antibody

Reactivity: Human, Mouse, Rat

Host: Rabbit

Applications: WB

Alternate Names: Interferon omega-1, Interferon alpha-II-1, IFNW1

Clonality: Polyclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: A synthetic peptide corresponding to residues in Human IFN-ω.

Dilution: WB: 1:500~1:1000

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Specificity: IFN-ω polyclonal antibody detects endogenous levels of IFN-ω protein.

Molecular Weight: ~ 20 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P05000

Product: Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Research Use Only