Product Description

Indoleamine 2, 3-dioxygenase Recombinant Rabbit mAb

Sizes: 50μl, 100μl

Catalogue Numbers: BS46653-50, BS46653-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: This gene encodes indoleamine 2, 3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on mμltiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregμlation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modμlates T-cell behavior by its peri-cellμlar catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011]

Category: Primary Antibody

Reactivity: Human

Host: Rabbit

Applications: WB, IHC, ICC/IF, FC, IP

Alternate Names: IDO, INDO, IDO-1

Clonality: Monoclonal

Conjugate: Unconjugated

Modification: Unmodification

Immunogen: Recombinant protein of human Indoleamine 2, 3-dioxygenase

Dilution: WB: 1:1000 IHC: 1:200 ICC/IF: 1:200 FC: 1:50 IP: 1:20

Purification: Affinity Purification

Specificity: IgG

Molecular Weight: 45 kDa

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

SwissProt: P14902

Product: Store at -20°C. Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. Stable for 12 months from date of receipt.

Research Use Only