Product Description

Integrin α6 Monoclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA11527-50, RA11527-100

Lead times: 1-2 weeks, if manufacturer has product in stock

Manufacturer/Ship Location: China

Background: integrin subunit alpha 6 (ITGA6) Homo sapiens The gene encodes a member of the integrin alpha chain family of proteins. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 6 subunit. This subunit may associate with a beta 1 or beta 4 subunit to form an integrin that interacts with extracellular matrix proteins including members of the laminin family. The alpha 6 beta 4 integrin may promote tumorigenesis, while the alpha 6 beta 1 integrin may negatively regulate erbB2/HER2 signaling. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015],

Reactivity: Human, Mouse, Rat, Bovine, Dog, Pig

Host: Mouse

Applications: WB, IF/ICC

Alternate Names: ITGA6, Integrin alpha-6, CD49 antigen-like family member F, VLA-6, CD antigen CD49f

Clonality: Monoclonal

Dilution: Western Blot: 1/1000 - 1/2000. Immunofluorescence: 1/100 - 1/500. Not yet tested in other applications.

Storage: -20°C/1 year

Condition: Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50% glycerol.

Human Gene ID: 3655

Research Use Only