Integrin β4 (phospho Tyr1510) Polyclonal Antibody - RA21121

Integrin β4 (phospho Tyr1510) Polyclonal Antibody

Sizes: 50μL, 100μL

Catalogue Numbers: RA21121-50, RA21121-100

Citations, Manuals and MSDS Available upon request.

Background: integrin subunit beta 4 (ITGB4) Homo sapiens Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

Condition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Instructions: -20°C/1 year

Recommended dilutions: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

Alternative Names: ITGB4; Integrin beta-4; GP150; CD antigen CD104

Applications: WB; IHC-p; IF (paraffin section) ; ELISA

Species Cross-Reactivity: Human; Mouse; Rat

GeneID (Human): 3691

Protein MW (KDa): 202

SWISS: P16144

Source: Rabbit

Research Use Only