Integrin β7 rabbit pAb - ES8849

Integrin β7 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES8849-50, ES8849-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms dimers with an alpha4 chain or an alphaE chain and plays a role in leukocyte adhesion. Dimerization with alpha4 forms a homing receptor for migration of lymphocytes to the intestinal mucosa and Peyer's patches. Dimerization with alphaE permits binding to the ligand epithelial cadherin, a calcium-dependent adhesion molecule. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013],

Alternate Name: Integrin beta-7 (Gut homing receptor beta subunit)

Source: Rabbit

Applications: WB; ELISA; IHC

Dilution: WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

Reactivity: Human; Mouse

Immunogen: Synthesized peptide derived from human Integrin β7. at AA range: 671-720

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 130kD

Human Gene ID: 3695

Human SWISS Prot NO: P26010

Subcellular Location: Membrane; Single-pass type I membrane protein.

Research Use Only